2011-2012 Basic and Clinical Science Course, Section 1: by Eric P. Purdy, MD

By Eric P. Purdy, MD

Covers systemic health conditions probably to impact ophthalmic sufferers, similar to infectious, metabolic, neurologic and cardiovascular illnesses; melanoma; and rheumatic and endocrine issues. contains a dialogue of preventive drugs and scientific emergencies, in addition to geriatrics and records. Ophthalmic issues are highlighted all through. comprises various up to date references and tables directory the names, symptoms and unintended effects of antibiotic, antihypertensive and anticancer medications. lately revised 2010 2011.

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The typical symptoms of which are fever, fatigue, weight loss, myalgias, headache, pharyngitis, and nausea_ Primary CHAPTER 1: Infectious Disease. 31 Tobl. 1-4 AIDS-Defining Conditions Bacterial infections, multiple or recurrent* Candidiasis of bronchi, trachea, or lungs Candidiasis of esophagust Cervical cancer, invasive§ Coccidioidomycosis, disseminated or extra pulmonary Cryptococcosis, extra pulmonary Cryptosporidiosis, chronic intestinal (> 1 month's duration) Cytomegalovirus disease (other than liver, spleen, or nodes), onset at age> 1 month Cytomegalovirus retinitis (with loss 01 vision)t Encephalopathy, HIV related Herpes simplex: chronic ulcers (>1 month's duration) or bronchitis, pneumonitis, or esophagitis (onset at age >1 month) Histoplasmosis, disseminated or extra pulmonary Isosporiasis, chronic intestinal (>1 month's duration) Kaposi sarcomat Lymphoid interstitial pneumonia or pulmonary lymphoid hyperplasia complex*t lymphoma, burkitt (or equivalent term) lymphoma, immunoblastic (or equivalent term) lymphoma, primary, of brain Mycobacterium avium complex or mycobacterium kansas;;, disseminated or extrapulmonaryt Mycobacterium tuberculosis of any site, pulmonary,t§ disseminated,t or extrapulmonaryt Mycobacterium, other species or unidentified species, disseminatedt or extrapulmonaryt Pneumocystis carinii pneumoniat Pneumonia.

Such as nevirapine (Viramune). also share the disadvantage of rapid emergence of viral resistance. Therefore. they are currently used in combination therapy. A newer NNRTI. efavirenz (Sustiva). is taken once daily. has excellent activity against HI\'; and has fewer side effects than other NNRTIs. This agent has become a cornerstone of antiretroviral therapy. and its efficacy over other antiretrovirals has been established in many clinical trials. ) is a new NNRTI and was granted accelerated approval in the United States and Europe in 2008.

Chronic mucocutaneous lesions may occur in persons with specific T-Iymphocyte defects. Disseminated disease can involve any organ system, most commonly the kidneys, brain, heart, and eyes, and is more common in immune-compromised patients and those with indwelling vascular catheters. Other important invasive fungal infections are cryptococcosis, histoplasmosis, blastomycosis, aspergillosis, and coccidioidomycosis. Invasive fungal infections have become a major problem in immunocompromised patients.

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