2011-2012 Basic and Clinical Science Course, Section 11: by James C. Bobrow MD

By James C. Bobrow MD

Experiences the anatomy, body structure, embryology and pathology of the lens. Covers the epidemiology, assessment and administration of cataracts; offers an outline of lens and cataract surgical procedure; and explores the issues and distinct occasions of cataract surgical procedure. final significant revision 2008 2009.

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Additional resources for 2011-2012 Basic and Clinical Science Course, Section 11: Lens and Cataract (Basic & Clinical Science Course)

Example text

See the secti on Pseudo exfo liation Syndrome.

The apices of the Single layer of cells are oriented toward the lumen of the lens vesicle. with the base of each cell attached to the capsule around the periphery of the vesicle. At the same time that the lens vesicle is forming, the optic vesicle is invaginati ng to form the 2-layered optic cup. Primary Lens Fibers and the Embryonic Nucleus The cells in the posterior layer of the lens vesicle stop dividing and begin to elongate. As they elongate. they begin to fill the lumen of the lens vesicle.

Still other studies have suggested that the passive membrane permeability to cations is increased with aging and cataract development. Pump-leak Theory The combination of active transport and membrane permeability is often referred to as the pump-leak system of the lens (Fig 3-1). According to the pump-leak theory, potas- Anterior Posterior (aqueous humor) (vitreous humor) Passive K+ ( ____ _ _ diffusion Inward active K+pump Outward active Na+transport Passive Na+ diffusion Inward active Ca 2 + pump <--- -----) <-<-<-- ) ---- - - -) ____) Passive diffusional exchange of H,O and solutes Inward active .

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